COVER STORY: Zheng et al. have developed a series of DNA methylation aging clocks on Chinese cohorts, providing valuable tools for measuring biological age and aging pace. Through an insightful analysis of the multiomics differences between individuals who exhibit accelerated aging and decelerated aging, they used multi-modal clocks to reveal the detrimental effects of lifestyle factors on aging pace. Furthermore, they have discovered a robust correlation between cytomegalovirus antibody levels and aging pace. Aging unfolds like a train on a track, with the circular track acting as a clock, mapping out the passage of time and life's stages.
Recollection
Protein & Cell, 2024, 15(8): 553-558
Boundless love: a German Professor Uli Schwarz
in China
Le Kang
Review
Protein & Cell, 2024, 15(8): 559-574
Skeletal stem cells in bone development, homeostasis, and disease
Guixin Yuan, Xixi Lin, Ying Liu, Matthew B. Greenblatt, Ren Xu
Research articles
Protein & Cell, 2024, 15(8): 575-593
DNA methylation clocks for estimating biological
age in Chinese cohorts
Zikai Zheng, Jiaming Li, Tianzi Liu, Yanling Fan, Qiao-Cheng Zhai, Muzhao Xiong, Qiao-Ran Wang, Xiaoyan Sun, Qi-Wen Zheng, Shanshan Che, Beier Jiang, Quan Zheng, Cui Wang, Lixiao Liu, Jiale Ping, Si Wang, Dan-Dan Gao, Jinlin Ye, Kuan Yang, Yuesheng Zuo, Shuai Ma, Yun-Gui Yang, Jing Qu, Feng Zhang, Peilin Jia, Guang-Hui Liu, Weiqi Zhang
Protein & Cell, 2024, 15(8): 594-611
Single-cell transcriptomic Atlas of aging macaque ocular outflow tissues
Jian Wu, Chaoye Wang, Shuhui Sun, Tianmin Ren, Lijie Pan, Hongyi Liu, Simeng Hou, Shen Wu, Xuejing Yan, Jingxue Zhang, Xiaofang Zhao, Weihai Liu, Sirui Zhu, Shuwen Wei, Chi Zhang, Xu Jia, Qi Zhang, Ziyu Yu, Yehong Zhuo, Qi Zhao, Chenlong Yang, Ningli Wang
Protein & Cell, 2024, 15(8): 612-632
Single-nucleus transcriptomics uncovers a geroprotective role of YAP in primate gingival aging
Qinchao Hu, Bin Zhang, Yaobin Jing, Shuai Ma, Lei Hu, Jingyi Li, Yandong Zheng, Zijuan Xin, Jianmin Peng, Si Wang, Bin Cheng, Jing Qu, Weiqi Zhang, Guang-Hui Liu, Songlin Wang
THE END
