3月18日,科技部通报了最新一批部分教育、医疗机构医学科研诚信案件调查处理结果,共计通报了54份处理通告,涉及9所高校,17家附属医院,超百人被处理。
此次很多案例处罚较为严厉,其中近20人被取消副主任医师、副教授职称,7人被撤销博士学位,10人终身不得申请认定研究生导师资格,4人被终身取消科技计划项目(专项、基金等)申报资格,还有多人被暂停研究生招生资格;取消博士学位申请资格等,降级、取消社会职务等。
这次共涉及9所高校,其中吉林大学(14篇),郑州大学(12篇),河南大学(7篇),哈尔滨医科大学(5篇),中山大学(5篇),新乡医学院(5篇),武汉大学(3篇),山东大学(2篇),黑龙江中医药大学大学(1篇)。
论文1:“Long non-coding RNA PVT1 promote LPS-induced septic acute kidneyinjury by regulating TNFαand JNK/NF-κB pathways in HK-2 cells”。
(通报链接:https://www.hrbmu.edu.cn/kyc/info/1026/1252.htm)
论文2:“Long non-coding RNA PVT1 promote LPS-induced septic acute kidneyinjury by regulating TNFαand JNK/NF-κB pathways in HK-2 cells”。
(通报链接:https://www.hrbmu.edu.cn/kyc/info/1026/1253.htm)
论文3:“Knockdown of long noncoding RNA Malat1 aggravates hypoxia-induced cardiomyocyte injury targeting miR-217”。
(通报链接:https://www.hrbmu.edu.cn/kyc/info/1026/1254.htm)
论文4:“Suppression of adriamycin resistance in osteosarcoma by blocking Wnt/β-catenin signal pathway”。
(通报链接:https://www.hrbmu.edu.cn/kyc/info/1026/1255.htm)
论文5:“Effects of miR-214 on cervical cancer cell proliferation, apoptosis and invasion via modulating PI3K/Akt/mTOR signal pathway”。
(通报链接:https://www.hrbmu.edu.cn/kyc/info/1026/1256.htm)
论文1:“Long noncoding RNA LINP1 promoted proliferation and invasion of ovarian cancer via inhibiting KLF6”。
(通报链接:http://www.ac.sdu.edu.cn/info/1073/1262.htm)
论文2:“Triptolide inhibits angiogenesis in microvascular endothelial cellsthrough regulation of miR-92a”。
经调查,该论文存在伪造、篡改研究数据、图表及不当署名的行为。
(通报链接:http://www.ac.sdu.edu.cn/info/1073/1262.htm)
论文1:“Long noncoding RNA RMRP upregulation aggravates myocardial ischemiareperfusion injury by sponging miR206 to target ATG3 expression”。
(通报链接:http://kjc.hljucm.net/info/1094/1243.htm)
论文1:“Long non-coding RNA LINC00978 promotes cell proliferation and tumorigenesis via regulating microRNA-497/NTRK3 axis in gastric cancer”。经调查,该论文存在代写、伪造研究数据、违反科研伦理、一稿多投行为。
(通报链接:http://xuefeng.sysu.edu.cn/gzdt/1398704.htm)
论文2:“Kaempferol inhibits proliferation, migration, and invasion of liver cancer HepG2 cells by down-regulation of microRNA-21”。
(通报链接:http://xuefeng.sysu.edu.cn/gzdt/1398704.htm)
论文3:“Down-regulation of microRNA-23b aggravates LPS-induced inflammatory injury in chondrogenic ATDC5 cells by targeting PDCD4”。
(通报链接:http://xuefeng.sysu.edu.cn/gzdt/1398704.htm)
论文4:“The effect of miR-224 down-regulation on SW80 cell proliferation and apoptosis and weakening of ADM drug resistance”。
(通报链接:http://xuefeng.sysu.edu.cn/gzdt/1398704.htm)
论文5:“SOCS3 overexpression enhances ADM resistance in bladder cancer T24 cells”。
经调查,该论文存在代写、伪造研究数据、虚假标注基金行为。
(通报链接:http://xuefeng.sysu.edu.cn/gzdt/1398704.htm)
论文1:“MiR-203 over-expression promotes prostate cancer cell apoptosis and reduces ADM resistance”。
(通报链接:http://xkjspt.znhospital.cn/tzgg/8840.jhtml)
论文2:“Involvement ofNORAD/miR-608/STAT3 axis in carcinostasis effects of physcion 8-O-β-GlucopyRanoside on ovarian cancer cells”。
(通报链接:http://www.rmhospital.com/a_overview/08_3_05.html)
论文3:“MicroRNA-641 inhibits lung cancer cells proliferation, metastasis but promotes apoptosis in cells by targeting PDCD4”。
(通报链接:http://www.rmhospital.com/a_overview/08_3_05.html)
论文1:“circSMAD2 governs migration and epithelial–mesenchymal transition by inhibiting micro RNA‐9”。
(通报链接:http://jluxfjs.jlu.edu.cn/content.jsp?urltype=news.NewsContentUrl&wbtreeid=1021&wbnewsid=1441)
论文2:“Ras–ERK1/2 signaling promotes the development of uveal melanoma by downregulating H3K14ac”。
(通报链接:http://jluxfjs.jlu.edu.cn/content.jsp?urltype=news.NewsContentUrl&wbtreeid=1021&wbnewsid=1441)
论文3:“Carcinogenic role of K-Ras-ERK1/2 signaling in bladder cancer via inhibition of H1.2 phosphorylation at T146”。
(通报链接:http://jluxfjs.jlu.edu.cn/content.jsp?urltype=news.NewsContentUrl&wbtreeid=1021&wbnewsid=1441)
论文4:“Neferine inhibits proliferation, migration and invasion of U251 glioma cells by down-regulation of miR-10b”。
(通报链接:http://jluxfjs.jlu.edu.cn/content.jsp?urltype=news.NewsContentUrl&wbtreeid=1021&wbnewsid=1453)
论文5:“KRas-ERK signalling promotes the onset and maintenance of uveal melanoma through regulating JMJD6-mediated H2A.X phosphorylation at tyrosine 39”。
(通报链接:http://jluxfjs.jlu.edu.cn/content.jsp?urltype=news.NewsContentUrl&wbtreeid=1021&wbnewsid=1453)
论文6:“The inhibitory function of icariin in cell model of benign prostatic hyperplasia by upregulation of miR-7”。
(通报链接:http://jluxfjs.jlu.edu.cn/content.jsp?urltype=news.NewsContentUrl&wbtreeid=1021&wbnewsid=1453)
论文7:“Knockdown of lncRNA HULC inhibits proliferation, migration, invasion and promotes apoptosis by sponging miR-122 in osteosarcoma”。经调查,该论文存在买卖论文数据的行为。
(通报链接:http://jluxfjs.jlu.edu.cn/content.jsp?urltype=news.NewsContentUrl&wbtreeid=1021&wbnewsid=1453)
论文8:“Ras-PI3K-AKT signaling promotes the occurrence and development of uveal melanoma by downregulating H3K56ac expression”。
(通报链接:http://jluxfjs.jlu.edu.cn/content.jsp?urltype=news.NewsContentUrl&wbtreeid=1021&wbnewsid=1453)
论文9:“IncRNA PEG10 promotes cell survival,invasion and migration by sponging miR-134 in human bladder cancer”。
(通报链接:http://jluxfjs.jlu.edu.cn/content.jsp?urltype=news.NewsContentUrl&wbtreeid=1021&wbnewsid=1453)
论文10:“Propofol inhibits proliferation, migration and invasion of gastric cancer cells by up-regulating microRNA-195”。
(通报链接:http://jluxfjs.jlu.edu.cn/content.jsp?urltype=news.NewsContentUrl&wbtreeid=1021&wbnewsid=1453)
论文11:“Salidroside protects ATDC5 cells against lipopolysaccharide-induced injury through up-regulation of microRNA-145 in osteoarthritis”。
(通报链接:http://jluxfjs.jlu.edu.cn/content.jsp?urltype=news.NewsContentUrl&wbtreeid=1021&wbnewsid=1453)
论文12:“Long non-coding RNA activated by transforming growth factor beta alleviates lipopolysaccharide-induced inflammatory injury via regulating microRNA-223 in ATDC5 cells”。
经调查,该论文存在编造研究过程,伪造研究数据、图表行为的行为。
(通报链接:http://jluxfjs.jlu.edu.cn/content.jsp?urltype=news.NewsContentUrl&wbtreeid=1021&wbnewsid=1453)
论文13:“Kaempferol protects chondrogenic ATDC5 cells against inflammatory injury triggered by lipopolysaccharide through down-regulating miR-146a”。
经调查,该论文存在编造研究过程,伪造研究数据、图表的行为。
(通报链接:http://jluxfjs.jlu.edu.cn/content.jsp?urltype=news.NewsContentUrl&wbtreeid=1021&wbnewsid=1453)
论文14:“Knockdown of microRNA-203 alleviates LPS-induced injury by targeting MCL-1 in C28/I2 chondrocytes”。
(通报链接:http://jluxfjs.jlu.edu.cn/content.jsp?urltype=news.NewsContentUrl&wbtreeid=1021&wbnewsid=1453)
论文1:“Silence of lncRNA ANRIL represses cell growth and promotes apoptosis in retinoblastoma cells through regulating miR-99a and cMyc”。
(通报链接:https://www.xxmu.edu.cn/kjc/info/1016/2427.htm)
论文2:“MiR-1246 Promotes LPS-Induced Inflammatory Injury in Chondrogenic Cells ATDC5 by Targeting HNF4γ”。
经调查,该论文存在伪造通讯作者邮箱、篡改数据和图片的行为。
(通报链接:https://www.xxmu.edu.cn/kjc/info/1016/2427.htm)
论文3:“MiR-125b Inhibits LPS-Induced Inflammatory Injury via Targeting MIP-1α in Chondrogenic Cell ATDC5”。
经调查,该论文存在伪造通讯作者邮箱、篡改数据和图片的行为。
(通报链接:https://www.xxmu.edu.cn/kjc/info/1016/2427.htm)
论文4:“Euxanthone suppresses tumor growth and metastasis in colorectal cancer via targeting CIP2A/PP2A pathway”。
(通报链接:https://www.xxmu.edu.cn/kjc/info/1016/2427.htm)
论文5:“Physcion 8-O-β-glucopyranoside alleviates oxidized low-density lipoprotein-induced human umbilical vein endothelial cells injury by inducing autophagy via AMPK/SIRT1 signaling”。
经调查,该论文存在伪造通讯作者邮箱、篡改数据和图片的行为。
(通报链接:https://www.xxmu.edu.cn/kjc/info/1016/2427.htm)
论文1:“LncRNA SNHG16 functions as an oncogene by sponging miR-200a-3p in pancreatic cancer”。
(通报网址:https://kyc.henu.edu.cn/info/1289/11812.htm)
论文2:“PHD2 acts as an oncogene through activation of Ras/Raf/MEK/ERK and JAK1/STAT3 pathways in human hepatocellular carcinoma cells”。
(通报网址:https://kyc.henu.edu.cn/info/1289/11812.htm)
论文3:“Inhibition of miR-221 influences bladder cancer cell proliferation and apoptosis”。
(通报网址:https://kyc.henu.edu.cn/info/1289/11812.htm)
论文4:“Geniposide suppresses growth, migration and invasion of MKN45 cells by down-regulation of lncRNA HULC”。
(通报网址:https://kyc.henu.edu.cn/info/1289/11812.htm)
论文5:“Lidocaine alleviates cytotoxicity-resistance in lung cancer A549/DDP cell via down-regulation of miR-21”。
(通报网址:https://kyc.henu.edu.cn/info/1289/11812.htm)
论文6:“Propofol exerts neuroprotective functions by down-regulating microRNA-19a in glutamic acid-induced PC12 cells”。
(通报网址:https://kyc.henu.edu.cn/info/1289/11812.htm)
论文7:“Ganoderic Acid A Protects Rat H9c2 Cardiomyocytes from Hypoxia-Induced Injury via Up-Regulating miR-182-5p”。
(通报网址:https://kyc.henu.edu.cn/info/1289/11812.htm)
论文:“MicroRNA-145 Aggravates Hypoxia-Induced Injury by Targeting Rac1 in H9c2 Cells”。
(通报网址:http://www.zzusah.com/2021/xuefengzhuanlan_0929/4276.html)
论文2:“Effects of microRNA-21 targetingPITX2 on proliferation and apoptosis of pituitary tumor cells”。
(通报网址:http://www.ztzy.com/NewsDetail-10569.html)
论文3:“Gastrodin protects rat cardiomyocytes H9c2 from hypoxia-induced injury by up-regulation of microRNA-21”。
(通报网址:http://www.zdyfy.com/newsss/vmsgisapi.dll/onemsg?msgid=2110041531056387700)
论文4:“MiR-29b aggravates lipopolysaccharide-induced endothelial cells inflammatory damage by regulation of NF-kappa B and JNK signaling pathways”。
(通报网址:http://www.zdyfy.com/newsss/vmsgisapi.dll/onemsg?msgid=2110041531576382946)
论文5:“LncRNA DIGIT Accelerates Tube Formation of Vascular Endothelial Cells by Sponging miR-134”。
(通报网址:http://www.zdyfy.com/newsss/vmsgisapi.dll/onemsg?msgid=2110041535086387349)
论文6:“MicroRNA-29a inhibits proliferation and motility of schwannoma cells by targeting CDK6”。
(通报网址:http://www.zdyfy.com/newsss/vmsgisapi.dll/onemsg?msgid=2110041536286381244)
论文7:“LncRNA GAS5 Overexpression Reverses LPS-Induced Inflammatory Injury and Apoptosis Through Up-Regulating KLF2 Expression in ATDC5 Chondrocytes”。
(通报网址:http://www.zdyfy.com/newsss/vmsgisapi.dll/onemsg?msgid=2110041537416384257)
论文8:“Sinomenine inhibits proliferation, migration, invasion and promotes apoptosis of prostate cancer cells by regulation of miR-23a”。
(通报网址:http://www.zdyfy.com/newsss/vmsgisapi.dll/onemsg?msgid=2110041541426382996)
论文9:“Arbutin attenuates hydrogen peroxide-induced oxidative injury through regulation of microRNA-29a in retinal ganglion cells”。
(通报网址:http://www.zdyfy.com/newsss/vmsgisapi.dll/onemsg?msgid=2110041542446381741)
论文10:“Long noncoding RNA SNHG15 enhances the development of colorectal carcinoma via functioning as a ceRNA through miR-141/SIRT1/Wnt/beta-catenin axis”。
(通报网址:http://www.zdyfy.com/newsss/vmsgisapi.dll/onemsg?msgid=2110041548286383524)
论文11:“MicroRNA-182 suppresses clear cell renal cell carcinoma migration and invasion by targeting IGF1R”。
(通报网址:http://www.zdyfy.com/newsss/vmsgisapi.dll/onemsg?msgid=2110041550336385453)
论文12:“Belinostat suppresses cell proliferation by inactivating Wnt/beta-catenin pathway and promotes apoptosis through regulating PKC pathway in breast cancer”和“Long Noncoding RNA CAMTA1 Promotes Proliferation and Mobility of the Human Breast Cancer Cell Line MDA-MB-231 via Targeting miR-20b”。
经调查,该2篇论文均存在伪造论文、不当署名的行为。
(通报网址:http://www.zdyfy.com/newsss/vmsgisapi.dll/onemsg?msgid=2110041551496387748)
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