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招聘（1648）Springer Lab at BCH博后

图灵基因

2024-12-23

导读：招聘（1648）Springer Lab at BCH博后

Employer

Springer Lab at BCH

Location

Boston, Massachusetts (US)

Salary

$78,000/annually + benefits

Closing date

Jan 11, 2025

Discipline

Life Sciences, Biochemistry, Biophysics, Immunology, Structural Biology, Health Sciences, Drug Discovery

Position Type

Full Time

Job Type

Postdoc

Organization Type

Academia

Join the Lab of Tim Springer
Tim Springer, a leader in integrin biology, invites aspiring scientists to join his lab to advance groundbreaking research in integrin transmembrane signaling, TGF-β activation, cell surface receptor mechanobiology, and therapeutic development. This role offers mentorship and opportunities to establish a strong scientific foundation for launching an independent research career.

About the Role:

As a Special Postdoctoral Fellow, you will:

·Pursue cutting-edge research in areas such as:

·Novel integrin ligands to drive stem cell and organoid development

·Cryo-EM: Activation of integrins and TGF-β, and ligand binding

·Mechanobiology: Integrin force transduction in rolling adhesion and firm adhesion and TGF-β activation

·Single Molecules: Utilize advanced techniques including FRET and magnetic tweezers to explore conformational change kinetics and force transmission in integrins and selectins

·Innovative ReaLiSM: (Receptor and Ligand in Single Molecules) to study receptor-ligand binding dynamics

·TGF-β Activation: Research localized activation at cell surfaces for new therapeutic targets

·Own and Develop Your Project: We encourage candidates to propose and develop their own research ideas, which they can carry forward to establish their own labs.

Key Techniques and Approaches:

·Single-molecule imaging

·Cryo-EM

·Organoid and stem cell research

·FRET reporters using non-canonical amino acids

·Magnetic and laser tweezers

·Mechanobiology and therapeutic target discovery

Why Join Us?

·Mentorship from Tim Springer, renowned for his pioneering work in integrins and cell biology

·Independence and Growth: Develop projects that will empower your transition to an independent research career

·Collaborative Environment at Harvard Medical School and Boston Children’s Hospital

Application Details:To apply, please email the following to springer_jobs@crystal.harvard.edu with "Special Postdoctoral Fellow" in the subject line:

1. Cover letter (include a brief outline of your project interests)

2. CV

3. Three references

Salary: $78,000 annually

Qualified applicants will receive consideration without regard to race, color, religion, national origin, sex, sexual orientation, gender identity, protected veteran status, or disability.

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