Model Organisms Research | 2026年第1期文章正式发布

Model Organisms Research（《模式生物研究》）是由北京生命科技研究院主办的一本跨学科、同行评议、开放获取的国际学术期刊。本刊以模式生物（包括模式植物、模式动物、模式微生物）研究为主题，致力于发表生命健康、生物医药、生物制造等前沿交叉领域具有重大突破性和创新性的研究成果，为全球相关领域科研人员搭建跨学科、国际化的高水平学术交流平台。期刊发表Research Article、 Review、Perspective 与Commentary等多种类型文章。

Model organisms research: The foundation for understanding, regulating, and engineering life

模式生物研究：认识生命、调控生命、设计生命的基石

The migratory locust (Locusta migratoria): A large-sized genome model for modern biology

飞蝗（Locusta migratoria）：现代生物学的大型基因组模型

Authors: Lili Cao^a, Qinghua Chen^a, Chaowei Zhang^b, Jing He^a , Ding Ding^a , Le Kang^a,b,*

a State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China

b Institute of Cell and Gene Technology, Shenzhen University of Advanced Technology, Shenzhen 518107, China

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Model microorganisms: From cornerstones of modern discovery to big data-driven platforms

模式微生物：从现代科学发现的基石到大数据驱动的研究平台

a State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Safety and Health; National Health Commission Science and Technology Innovation Platform for Nutrition and Safety of Microbial Food, Key Laboratory of Big Data Technologies for Food Microbiological Safety, State Administration for Market Regulation, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou 510070, China

b Food and Drug Laboratory, Guangdong Detection Center of Microbiology, Guangzhou 510070, China

c Guangdong Huankai Biology Sci.&Tech. Co., Ltd, Zhaoqing 510663, China

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Nicotiana benthamiana: From model plant to biofactory chassis

本氏烟草：从模式植物到植物生物制造底盘

Authors: Xiaotong Wang^a,b , Xiaodong Xie^a,b , Guoxin Chen^a,b , Yuanyuan Huang^a,b , Jianfeng Zhang^a,b ,Peijian Cao^a,b,*

a Beijing Life Science Academy, Beijing 102209, China

b Key Laboratory of Biosynthesis and Biomanufacturing in Model Plants, Ministry of Industry and Information Technology, Beijing 102209, China

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Neuroinflammation-targeted natural products for the therapy of Alzheimer’s disease

靶向神经炎症的天然产物作为阿尔茨海默病的治疗药物

Authors: *Sirakawin Chaweewan^a,b,c , Kun Cui^a, , Yuchen Zhang^a , Jian Mao^a,⁎, , Jie Zheng^{b,c, ⁎⁎}, You Wan^{a,b,c,⁎⁎⁎}

a Beijing Life Science Academy, Beijing 102209, China

b Key Laboratory for Neuroscience, Ministry of Education/National Health Commission, Peking University, Beijing 100191, China

c Neuroscience Research Institute and Department of Neurobiology, School of Basic Medical Sciences, Peking University, Ministry of Education/National Health Commission, Peking University, Beijing 100191, China

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Plant synthetic biology: From modular design to artificial intelligence-driven engineering

植物合成生物学：从模块化设计到人工智能驱动的工程

Authors: Qiang Guo^a , Ci Kong^b,c , Jianfeng Zhang^b,c , Peijian Cao^b,c , Shuai Fu^d,⁎, Baojun Wang^a,b,c,⁎⁎

a Key Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310058, China

b Beijing Life Science Academy, Beijing 102209, China

c Key Laboratory of Biosynthesis and Biomanufacturing in Model Plants (Beijing Life Science Academy), Ministry of Industry and Information Technology, Beijing 102209, China

d Research Center for Life Sciences Computing, Zhejiang Lab, Hangzhou 310058, China

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Recent research progress of plant-derived chlorogenic acid in cancer therapy: Anticancer mechanism and combination therapy

绿原酸在癌症治疗中的最新研究进展：抗癌机制与联合治疗

Authors: Liting Qin^a , Junlan Cai^a,^*, Peng Lu^a,b , Yong Chen^a , Hongliang Lu^c , Runtong Hou^a , Xiang Li^a ,Yigai Pan^a,d , Junwei Zhao^a , Yanjun Huang^a,c , Peng Li^a , Yan Chen^e , Jinbang Wang^b , Tietuo Tao^a,*，Shaofeng Liu^a,*

a Beijing Life Science Academy, Beijing 102209, China

b Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou 450001, China

c China Tobacco Fujian Industrial Co., Ltd., Xiamen 361021, China

d China Tobacco Guangxi Industrial Co., Ltd., Nanning 530001, China

e China Tobacco Guangdong Industrial Co., Ltd., Guangzhou 510385, China

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Phytochrome B and CIPK31 coordinate VOZ2-dependent gibberellic acid signaling in rice

光敏色素PhyB与CIPK31协同调控水稻中VOZ2依赖的赤霉素信号

Authors: Huan Chen^a,b , Depeng Yuan^b , Ci Kong^a , Peijian Cao^a,c , Jingjing Jin^a,c , Yuan Hu Xuan^a,b,⁎

a Beijing Life Science Academy, Beijing 102209, China

b State Key Laboratory of Elemento-Organic Chemistry and Department of Plant Protection, National Pesticide Engineering Research Center (Tianjin), College of Chemistry,

Nankai University, Tianjin 300199, China

c China Tobacco Gene Research Center, Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou 450001, China

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Postnatal deletion of ZIP9 leads to premature mortality and hippocampal-dependent cognitive decline with disrupted brain–gut–lipid homeostasis

出生后敲除ZIP9扰乱小鼠脑-肠-脂质稳态，导致小鼠过早死亡和海马依赖性的认知衰退

Authors: Chenyan Zheng^a , Yumeng Ma^a , Zihan Wang^a , Yifei Wang^a , Le Cheng^a , Yaqiong Liu^a , Xiaoting Hao^a , Xinlei Yuan^a , Tuo Zhang^b , Bing Fang^a,c,*

a Key Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100093, China

b College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100093, China

c Food Laboratory of Zhongyuan, Luohe 462300, Henan, China

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Foliar ZnO NPs trigger transcriptional rewiring of starch and hormone pathways to break the yield-quality trade-off in direct-seeded rice

氧化锌纳米颗粒触发淀粉和激素通路转录重组，打破直播水稻产量品质权衡

Authors: Jintao Shang^a,b , Shaojie Song^a , Shuyu Ye^b , Yuanbo Zeng^c , Ning Fang^d , Mingding Qu^a ，Zhong Wang^b,*, Shiquan Bian^a,*

a Rice Research Institute, Anhui Academy of Agricultural Sciences, Hefei 230031, China

b Agricultural Technology Extension Center of Linping District, Hangzhou 311199, China

c Longping Agricultural College, Hunan University, Changsha 41000, China

d Henan Academy of Sciences, Zhengzhou 410125, China

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