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The Bruker Philosophy for Preclinical Imaging
For preclinical MRI Bruker has embraced a unique philosophy to ensure that we understand our customers’ needs and the challenges they face, and that best utilizes our expertise and knowledge. To deliver on this approach Bruker has installed, in-house, eight installed preclinical MRI systems of different bore sizes and field strengths from 1 to 15 Tesla (T)
at our main application facility in Ettlingen, Germany.
Supported by many application specialists that cover every application, their trusted expertise and knowledge is what drives the development of innovative in vivo imaging applications. The resulting solutions benefit a wide range of demanding needs in preclinical imaging, molecular medicine, biomedical and pharmaceutical research. It is this same
knowledge and expertise that is made available to individual projects and collaborative developmental efforts.
By developing MRI instrumentation in-house on in vivo subjects, the number of unnecessary animal experiments at customer sites is significantly reduced, as is the time required before customers can produce their own data.
The Applications Center has fully optimized protocols for fMRI, DTI, Perfusion, Cardiology, Angiography, Abdomen, Anatomy, IntraGate (Self-Gating), Relaxometry, and Spectroscopy all of which have been developed in vivo in-house, for use with mice and rats across our entire MRI product range, namely BioSpec ® , PharmaScan ® , ClinScan ® and Icon. These protocols have been developed for all field strengths from 1 T to 15.2 T with the appropriate gradient and RF coils. There are more than 600 protocols available that can be used ‘out of the box’.
Traditionally such powerful technology required years of expertise, intensive training or specialist operators, but today an MRI system from Bruker does all the complex work for you. You focus on your biological, pharmaceutical and preclinical investigations - we’ll take care of the rest.
Angiography
Examine the finest vessels with Bruker’s Time of Flight (TOF) and Phase Contrast Angiography (PCA)
No need for contrast agents
For all of your pathological questions, all throughout the body
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Qualitative and quantitative analysis
Cardiology
Bruker meets the ultimate challenge in MR Imaging with its unsurpassed cardiac imaging
Four chamber black blood to locate defects of the septum
Two chamber bright blood for investigation of ejection fraction
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Short axis tagging for assesment of wall motion
Diffusion
Achieve highest resolution and best possible sensitivity with Bruker’s diffusion options
Measure diffusion weighted images, diffusion tensor images, trace images, fractional anisotropy images,
and apparent diffusion coefficient maps
Acquire highest possible sensitivity in diffusion weighted images with Bruker’s world-wide strongest gradients
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Obtain critical information about tumor infiltration, cardiac infarction, connectivity, stroke, and more
fMRI
Where are they thinking? Find out with Bruker’s fMRI
From visual stimulation to conditioned taste aversion
The speed you need for fMRI
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Integrated evaluation tool
