New insights into brain function with molecular and functional MRI of the rodent brain at ultra-high fields
Chemical exchange saturation transfer (CEST) is a molecular imaging technique used in 1H magnetic resonance imaging (MRI) for pre-clinical and translational research that particularly benefits from ultra-high fields. Combined with fMRI measurements that prove for the first time that the BOLD signal exhibits a supra-linear increase even at ultra-high field strength, the increased sensitivity and specificity allows new insights into brain function.
Key points
In this webinar, MR physicist Prof. Seong-Gi Kim and market product manager Tim Wokrina from Bruker BioSpin will discuss:
How the massive increase of the chemical exchange effect for the amine proton signal by 65% in rat brain at 15.2 Tesla compared to 9.4 Tesla offers higher molecular sensitivity and specificity with reduced overlap of background signals.
How ultra-high field fMRI significantly increases the sensitivity of blood oxygen level dependent (BOLD) imaging of the rodent brain.
Prof Kim’s data shows a never seen before high BOLD effect, enabling faster measurements, higher specificity, and allows perfect correlation with other physiological parameters.
How ultra-high fields will achieve new insights into the function of the brain.
How the massive increase of the chemical exchange effect for the amine proton signal by 65% in rat brain at 15.2 Tesla compared to 9.4 Tesla offers higher molecular sensitivity and specificity with reduced overlap of background signals.
How ultra-high field fMRI significantly increases the sensitivity of blood oxygen level dependent (BOLD) imaging of the rodent brain.
Prof Kim’s data shows a never seen before high BOLD effect, enabling faster measurements, higher specificity, and allows perfect correlation with other physiological parameters.
How ultra-high fields will achieve new insights into the function of the brain.
Join the discussion on Thursday December 14, Register Now!
Your Webinar Team
When and Where
Session 1: 09.00am CET / 05.00pm KST
Session 2: 11.00am EST / 05.00pm CET
Prof. Seong-Gi Kim Director of Center for Neuroscience Imaging Research, Institute for Basic Science; Professor of Biomedical Engineering, Sungkyunkwan University Suwon, Korea
Dr. Tim Wokrina Market Product Manager MRI Bruker BioSpin MRI Mannheim Area, German
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