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From Concept to Lab Reality
MPI is a tomographic imaging technique that detects the magnetic properties of injected iron-oxide nanoparticles.
The new technology, invented by Philips, and frst introduced in a 2005 Nature paper, gave rise to high aspirations for a new era in biological imaging.
Now Bruker has combined its expertise in technological innovation with its passion for pushing the boundaries of understanding, and launched the previously only envisioned possibilities to the imaging community.
Unimagined Speed and Sensitivity
1,000 Times Faster Than PET
With Bruker‘s MPI imaging of up to 46 volumes per second can be performed, allowing real time imaging of biological processes at an equal or higher spatial
resolution than with PET.
Total Animal Visualization Flexibility
MPI measures the 3D distribution of injected iron oxide nanoparticles using a 25 kHz RF signal. This signal can easily be recorded from any depth within the animal allowing complete flexiblity in choosing areas of interest.
Pure Sensitivity
MPI images only injected ino-oxide nanoparticles, so there is no background signal.
100% User-Friendly
Bruker’s MPI System incorporates ParaVision® 6 and accommodates Bruker‘s multi-modal bed, providing a seamless transition of your animal to and from your Bruker MRI system.
Novel Applications Come to Life
The ability to acquire high time-resolution images within a single second allows for novel applications in medical and industrial research and ultimately patient care in which temporal resolution is key.
A World of New Possibilities
Cardio-Vascular
• Cardiac ejection fraction, wall motion, flow dynamics
• Coronary blood supply
• Quantitative myocardial perfusion
• Vulnerable plaque detection
Interventional Radiology (3D)
• Stent placement
• Catheter navigation
Oncology
• Micro-vascularization (blood volume)
• Inflow-outflow kinetics (Pharmacokinetics)
• Interventional oncology
• Ablation monitoring
• Highly localized heating for therapy and thermal triggering of local drug release
Neuro-Vascular
• Bleeding detection
• Functional brain imaging
Cell Tracking
• White blood cell tracking – inflammation detection
• Therapeutic (stem) cell tracking
Breast Imaging
• Sentinel lymph node detection
• Screening
Organ Perfusion Imaging
• Liver perfusion
• Lung perfusion (incl. therapy response assessment)
• Lung ventilation
The World‘s First Preclinical MPI System
The World‘s First Preclinical MPI System
Magnetic Particle Imaging (MPI) has been heralded as a future preclinical imaging technique with the potential to revolutionize disease studies, translational research, and drug discovery. For some, that potential is a pipe-dream; to Bruker and its partner and MPIinventor Royal Philips, that dream has arrived.
Meet the world’s frst commerical MPI system, now available to order for your own imaging lab.
Partnering in Innovation
The result of an exclusive collaboration, the MPI system combines Bruker’s leading expertise in analytical magnetic resonance instruments and preclinical Magnetic Resonance Imaging (MRI) with Philips’ unique strengths in medical imaging.
MPI is a completely new preclinical imaging technique with enormous potential to deliver new insights into disease processes at the organ, cellular, and molecular level.
With the new MPI system, Bruker further complements its extensive preclinical imaging product portfolio that includes MRI, PET, SPECT, micro-CT, optical molecular imaging, and X-ray.
Features
• Powerful drive, selection, and focus field technologies
• ParaVision® acquisition and processing platform with DICOM export and import
• Full 3D imaging and segmented acquisition capability
• Bolus injection triggering via ParaVision®
• Bruker’s multi-modality animal handling system
• 12 cm free access for imaging of mice, rats, guinea pigs, and rabbits
• Bruker AVANCE III / MPI technology
• Recommended morphology reference: Desktop MRI ICON™
Innovation You Can Trust
Offering the largest range of preclinical imaging systems, with an unmatched 9 in-vivo modalities, Bruker is committed to supporting the scientific community with high-end instruments dedicated to disease research, translational science, and molecular imaging.
Benefiting from more than 5 decades of passionate innovation, Bruker‘s customers profit from the vast portfolio of modalities from a single source, providing endless opportunities to combine multiple modalities for seamless workflows and higher productivity. These non-invasive in-vivo imaging modalities are based on animal-centric solutions to deliver the greatest scientific insight.
Your Personal Partner
Bruker provides customized support and service designed to make your instrumentation choice and subsequent installation of cutting edge technology a smooth and welcoming experience.
You can expect the highest quality of support starting with the acquisition process and continuing throughout the lifetime of your chosen solution.
From the initial site evaluation, through the system installation, and for the entire lifetime of your instrument, Bruker’s service program is dedicated to providing personalized support.
Welcome to the Community
Bruker’s commitment to the imaging community means that we play an active role in supporting, strengthening, and innovating.
You can rely on Bruker to deliver informative user support programs, from a regular presence at international events, to users’ meetings, symposiums and workshops, and expanded interaction at social and networking opportunities.
