Powerful Anti-Inflammatory Benefits of Olive Oil | 橄榄油具有强大的抗炎功效

Powerful Anti-Inflammatory Benefits of Olive Oil

橄榄油具有强大的抗炎功效

Extra virgin olive oil (EVOO) contains more than 36 phenolic compounds. Although all of the phenolic compounds in EVOO have known beneficial effects, one specific compound in particular, known as oleocanthal, has been discovered to have powerful natural anti-inflammatory benefits.

特级初榨橄榄油含有超过36种酚类化合物。虽然EVOO中所有的酚类化合物都已经知道了有益的作用，但是一种特殊的化合物，被称为Oleocanthal，已经被发现具有强大的天然抗炎作用。

In fact, oleocanthal exhibits the same anti-inflammatory response in the body as NSAID ibuprofen, acting down the exact same pathways as a non-steroidal anti-inflammatory. Oleocanthal has been shown to stop the inflammatory cascade by inhibiting both cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) inflammatory enzymes in a dose-dependent manner.

事实上，Oleocanthal在体内表现出与非甾体类抗炎药异布洛芬一样的抗炎反应，作用于与非甾类抗炎药相同的途径。烯花青素通过抑制环氧化酶-1 (COX-1)和环氧化酶-2 (COX-2)的炎症酶来抑制炎症级联反应。

Compared to NSAID ibuprofen, its potency is less, at approximately 10 percent. However, unlike NSAIDs, which have many known side effects, olive oil is a natural anti-inflammatory agent that can be safely consumed by anyone.

与NSAID ibuprofen相比，它的效力更低，约为10%。然而，与有许多已知副作用的非甾体抗炎药不同，橄榄油是一种天然的抗炎剂，任何人都可以放心食用。

According to a study in the International Journal of Molecular Science, “The concentration of oleocanthal contained in virgin olive oil ranges from 284 to 711 mg/kg.” And oleocanthal is unique only to olive oil. It is not found in any other vegetable oils.

根据《国际分子科学杂志》上的一项研究，“初榨橄榄油中含有的油色素浓度在284 - 711毫克/公斤之间。”只有橄榄油才有花青素。它不存在于任何其他植物油中。

It has been well established in research that the pathophysiology of many different disease states such as cancer, cardiovascular disease, arthritis, neurodegenerative disease, and others, are associated with low-grade chronic inflammation in the body.

研究表明，许多不同疾病状态的病理生理学，如癌症、心血管疾病、关节炎、神经退行性疾病等，都与体内的低级别慢性炎症有关。

Both in vivo and in-vitro research has reported that EVOO reduces the inflammatory response in the body, and therefore, may reduce the pathogenesis and development of many of these chronic diseases. Again, oleocanthal has been attributed to such results in many instances.

体内和体外研究均报道，EVOO降低了体内炎症反应，因此，可能会减少许多慢性疾病的发病和发展。再一次，在许多情况下，油膜花被认为是这样的结果。

Some of the powerful natural anti-inflammatory benefits of EVOO and oleocanthal reported in relation to the conditions mentioned above, include:

特级初榨橄榄油和oleocanthal的一些强大的天然抗炎作用与上述的条件有关，包括:

1. Cancer

癌症

Oleocanthal has anti-prolific effects on breast and prostate cancer cell lines and promotes cancer cell death (apoptosis). It’s been shown to down regulate COX-2 expression in colon cancer cells. EVOO has been shown to reduce tumor necrosis factor alpha (TNF-a) and COX-2 in glioblastoma cells, one of the most aggressive types of brain cancers that frequently results in early death. And, studies have also shown EVOO consumption reduces the risk of prostate, lung, larynx, ovary, breast, and colon cancers.

Oleocanthal对乳腺癌和前列腺癌细胞有抑制作用，促进癌细胞死亡(细胞凋亡)。它被证明可以降低COX-2在结肠癌细胞中的表达。在胶质母细胞瘤细胞中，EVOO被证明可以减少肿瘤坏死因子alpha (TNF-a)和COX-2，这是一种最具侵略性的脑癌，经常导致早期死亡。此外，研究还表明，服用EVOO可以降低患前列腺癌、肺癌、喉癌、卵巢癌、乳腺癌和结肠癌的风险。

2. Cardiovascular Disease

心血管疾病

Among other benefits, EVOO has been shown to down regulate inflammatory genes implicated in atherosclerosis. Change the status of oxidative stress, inflammation, lipid peroxidation, and lipid profile in coronary artery disease. And prevent a compound called trimethylamine N-oxide (TMAO) that has been linked to higher risk for atherosclerosis, heart attacks, heart failure, and strokes.

在其他好处中，特级初榨橄榄油已经被证明可以降低与动脉粥样硬化相关的炎症基因。改变冠状动脉疾病的氧化应激、炎症、脂质过氧化和脂质谱。预防一种叫做三甲基胺n -氧化物(TMAO)的化合物，它与动脉粥样硬化、心脏病发作、心力衰竭和中风的高风险有关。

3. Arthritis

关节炎

Oleocanthal attenuates inflammatory mediators that result in degenerative joint disease, acting on both local inflammation in cartilage and on the inflammatory cascade in synovial cells, slowing down the inflammatory and degeneration process. It’s also been shown to reduce arthritic pain by reducing prostaglandin production. And, the anti-inflammatory actions exert powerful effects on key immune cells known as macrophages, therefore it is thought to be beneficial for osteoarthritis and rheumatoid arthritis also.

Oleocanthal的作用是减弱导致关节退行性疾病的炎症介质，作用于软骨的局部炎症和滑膜细胞的炎性级联，减缓炎症和退变过程。它还被证明可以通过减少前列腺素的产生来减少关节炎疼痛。抗炎作用对巨噬细胞的主要免疫细胞有强大的作用，因此也被认为对骨关节炎和类风湿关节炎有益。

4. Neurodegenerative Diseases

神经衰退性疾病

Oleocanthal has been shown to prevent the development of lesions associated with Alzheimer’s disease and has also been shown to reduce the formation of beta-amyloid senile plaques in the brain, which are thought to be involved in the initiation of Alzheimer’s. The anti-inflammatory components of EVOO have also been shown to scavenge pesticide induced free radicals that contribute to neurological disorders such as Alzheimer’s and Parkinson’s.

Oleocanthal已经被证明可以阻止与阿尔茨海默病相关的病变的发展，并且已经被证明可以减少大脑中-淀粉样蛋白老年斑的形成，这些斑块被认为与阿尔茨海默病的发生有关。EVOO的抗炎成分也被证明可以清除农药引发的自由基，这些自由基会导致老年痴呆症和帕金森氏症等神经系统疾病。

In relation to the natural anti-inflammatory capacity of EVOO, the benefits reported here are just a small proportion of the what’s available in the scientific literature. There are many more studies showing positive association for other health conditions that have not been mentioned.

相对于EVOO的天然抗炎能力，这里所报道的益处只是科学文献中可获得的一小部分。有更多的研究表明，其他健康状况与健康状况之间存在着积极的联系，但这一点尚未被提及。

Although oleocanthal is the most strongly reported anti-inflammatory phenolic compound, others have also been recorded. Oleuropein aglycone inhibits the proinflammatory molecule TNF-a. Hydroxytyrosol has been shown to reduce TNF-a and interleukin-1 beta with promising effects on other key proinflammatory molecules. Tyrosol has been shown to inhibit COX-2.

虽然油色素是最强烈报道的抗炎酚化合物，其他也有记录。烯尿苷苷苷无糖基对促炎分子TNF-a的抑制作用。羟基酪氨酸已经被证明可以减少TNF-a和白介素-1 - beta，对其他关键的促炎分子有很好的效果。Tyrosol被证明可以抑制COX-2。

Interestingly, many of the studies conducted show these anti-inflammatory effects to be in a dose-dependent manner, which presents a strong case that more EVOO consumption is beneficial for reducing the inflammatory effects of many chronic and deadly diseases. Best of all, it’s a natural, affordable and safe alternative that can be included in an individual’s everyday dietary routine.

有趣的是，许多研究表明这些抗炎作用是以剂量依赖的方式进行的，这有力地证明了更多的EVOO消费有利于减少许多慢性和致命疾病的炎症效应。最重要的是，它是一种自然的、负担得起的、安全的选择，可以被纳入个人的日常饮食习惯中。

△  第岚特级初榨橄榄油Tierra De Olivos 

Resource from: Olive Oil Times by Jedha Dening

Picture：Pinterest & OOT