特色产品
1
🔗 PTMScan® O-GlcNAc [GlcNAc-S/T] Motif Kit #95220
O-GlcNAcylization是一种新兴的翻译后修饰（PTM），研究热度逐年增加。研究认为，O-GlcNAcylization被认为是一种营养和应激传感器，调节从转录和翻译到信号转导和代谢的细胞过程。生理学上，O-GlcNAc稳态的破坏与许多人类疾病的发病机制有关，包括癌症、糖尿病和神经退行性变（1）。
产品介绍：
PTMScan® O-GlcNAc糖基化修饰组学研究试剂盒采用 Cell Signaling Technology (CST) 的专有方法通过免疫沉淀实现肽富集，这种方法使用一种特殊微珠偶联抗体以及液相色谱法 (LC)-质谱法 (MS/MS) 对细胞蛋白中的O-GlcNAc糖基化修饰位点进行定量分析。PTMScan® 技术能让研究人员分离、鉴定以及定量大量O-GlcNAc糖基化修饰的细胞肽，从而可以全面了解细胞和组织样品中的O-GlcNA糖基化修饰，对这些修饰位点发生于何处不会具有偏好性。
使用通过 PTMScan® O-GlcNAc [GlcNAc-S/T] Motif Kit富集和鉴定的胰蛋白酶肽进行 Motif 分析。用胰蛋白酶消化经10 μM Thiamet-G（TMG）处理 6 小时的10 mg HeLa 细胞，并用 PTMScan ® O-GlcNAc [GlcNAc-S/T] 免疫亲和微珠进行免疫沉淀分析。Orbitrap Fusion™ Lumos™ 质谱仪分析共确定了 1,235 个不重复位点。
2
🔗 Human Exhausted CD8+ T Cell IHC Antibody Sampler Kit #43049
产品介绍：
Human Exhausted CD8+ T Cell IHC Antibody Sampler Kit 提供了一种经济的方法，可表征福尔马林固定、石蜡包埋的组织样品中CD8+ T 细胞的耗竭程度。
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3
🔗 Human Exhausted T Cell Antibody Sampler Kit #81490
产品介绍
Human Exhausted T Cell Antibody Sampler Kit 提供了表征 T 细胞衰竭程度的多个小包装抗体组合。该试剂盒包含足够的抗体，可以对每种一抗进行两次蛋白质印迹分析。
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4
🔗 IFN (Type I/III) Signaling Pathway Antibody Sampler Kit #35114
产品介绍：
IFN (Type I/III) Signaling Pathway Antibody Sampler Kit 为使用磷酸化特异性抗体和对照抗体检测 IFN（I/III 型）信号转导通路的激活提供了一种经济的方法。该试剂盒包含的抗体足以使用每种一抗进行两次蛋白印迹实验。
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5
🔗 IFN-γ Signaling Pathway Antibody Sampler Kit #44902
产品介绍
IFN-γ Signaling Pathway Antibody Sampler Kit 提供了一种经济的方法，可使用磷酸特异性抗体和对照抗体检测 IFN-γ 信号转导通路的激活。该试剂盒包含的抗体足以使用每种一抗进行两次蛋白印迹实验。
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规格 |
应用 |
反应种属 |
Adhesion/ECM |
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MUC16 (IHC125) Mouse mAb |
100µl |
W IHC-Bond IHC-P |
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Syndecan 1 (IHC138) Mouse mAb |
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Phospho-PI3 Kinase p85 (Tyr458)/p55 (Tyr199) (E3U1H) Rabbit mAb (Alexa Fluor® 488 Conjugate) |
100µl |
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81913S |
Phospho-PI3 Kinase p85 (Tyr458)/p55 (Tyr199) (E3U1H) Rabbit mAb (Alexa Fluor® 647 Conjugate) |
100µl |
F |
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79409S |
SRPK2 Antibody |
100µl |
W IP |
H M R Mk |
Apoptosis |
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17416S |
Lamin B1 (E6M5T) Rabbit mAb |
100µl |
W IHC-P |
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10188T |
RIP3 (E7A7F) XP® Rabbit mAb |
20µl |
W IP IHC-P IF-IC F |
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10188S |
RIP3 (E7A7F) XP® Rabbit mAb |
100µl |
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29382S |
Atg13 (D4P1K) Rabbit mAb (Biotinylated) |
100µl |
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40592S |
Phospho-Atg4B (Ser383) (E3I8M) Rabbit mAb |
100µl |
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Phospho-PLCγ2 (Tyr759) (E9E9Y) Rabbit mAb |
100µl |
W |
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Cell Cycle / Checkpoint Control |
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49604S |
Cyclin D1 (E3P5S) XP® Rabbit mAb (Alexa Fluor® 647 Conjugate) |
100µl |
F |
H M R |
Chromatin Regulation / Nuclear Function |
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43345S |
HLTF Antibody |
100µl |
W IP |
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100µl |
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15793S |
MTA2 Antibody |
100µl |
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H M R Mk |
Cytoskeletal Signaling |
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81681S |
MRCKα (E2S5I) Rabbit mAb |
100µl |
W IP IF-IC |
H M R |
86980S |
NUP62 Antibody |
100µl |
W IP |
H |
Developmental Biology |
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84638S |
CDX2 (D11D10) Rabbit mAb (Alexa Fluor® 555 Conjugate) |
100µl |
IF-IC |
H |
66309S |
GATA-4 (D3A3M) Rabbit mAb (Alexa Fluor® 647 Conjugate) |
100µl |
IF-IC F |
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66670S |
GLI2 (E7R1N) Rabbit mAb |
100µl |
W IP |
H |
90904S |
TCF1/TCF7 (C63D9) Rabbit mAb (Alexa Fluor® 700 Conjugate) |
100µl |
F |
H M |
Immunology and Inflammation |
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49888S |
C9orf7/CACFD1 Antibody |
100µl |
W |
H |
43049T |
Human Exhausted CD8+ T Cell IHC Antibody Sampler Kit |
1Kit |
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72031S |
CD57 (HNK-1) Mouse mAb |
100µl |
IHC-Bond IHC-P IF-IC |
H |
24595T |
CD206/MRC1 (E6T5J) XP®Rabbit mAb |
20µl |
W IP IHC-Bond IHC-P IF-F |
H M R |
24595S |
CD206/MRC1 (E6T5J) XP®Rabbit mAb |
100µl |
W IP IHC-Bond IHC-P IF-F |
H M R |
84287S |
PhosphoPlus® CrkL (Tyr207) Antibody Duet |
1Kit |
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45597S |
CXCL1/CXCL2 (E5M6D) Rabbit mAb (Biotinylated) |
100µl |
W |
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54390S |
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100µl |
W |
H |
73235S |
ISG20 Antibody |
100µl |
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35114T |
IFN (Type I/III) Signaling Pathway Antibody Sampler Kit |
1Kit |
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44902T |
IFN-γ Signaling Pathway Antibody Sampler Kit |
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IRF-8 (D20D8) Rabbit mAb (Biotinylated) |
100µl |
W |
H M |
39475T |
IL-2Rα/CD25 (E9W2J) XP® Rabbit mAb |
20µl |
W IP IHC-Bond IHC-P IF-F F |
M |
39475S |
IL-2Rα/CD25 (E9W2J) XP® Rabbit mAb |
100µl |
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W IP |
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Mouse IL-12 Recombinant Protein |
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Human Exhausted T Cell Antibody Sampler Kit |
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C/EBPα (D56F10) XP® Rabbit mAb (Biotinylated) |
100µl |
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100µl |
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Motif Antibodies |
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PTMScan®O-GlcNAc [GlcNAc-S/T] Motif Kit |
1Kit |
/ |
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Neuroscience |
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ApoE4 (E5M4L) Rabbit mAb |
100µl |
W IHC-P |
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96540S |
DBN1 Antibody |
100µl |
W |
H M R |
91617S |
HIP1R Antibody |
100µl |
W IP |
H M R |
62141S |
ITM2A Antibody |
100µl |
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KCNK6 Antibody |
100µl |
W IP |
H M |
47990S |
TRIM9 Antibody |
100µl |
W |
H M R |
Nuclear Receptor Signaling |
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61460S |
RUFY3 Antibody |
100µl |
W IP |
H M R |
Protein Folding and Trafficking |
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38241S |
ACE2 (E9G3S) Mouse mAb |
100µl |
W IHC-Bond IHC-P |
H M |
70592S |
GCN2 (E7G7E) Rabbit mAb (Biotinylated) |
100µl |
W |
H |
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27287S |
100X Spermidine |
1.3ml |
C&R |
/ |
48105S |
CUT&RUN 4X Stop Buffer |
1ml |
C&R |
/ |
31415S |
CUT&RUN 10X Wash Buffer |
15ml |
C&R |
/ |
15338L |
CUT&RUN Antibody Binding Buffer |
5ml |
C&R |
/ |
42015S |
CUT&RUN DNA Extraction Buffer |
7ml |
C&R |
/ |
55494S |
GFP (5G4) Mouse mAb |
100µl |
IP IF-IC |
All |
63707S |
SignalStain® Boost IHC Detection Reagent (HRP Goat) |
15ml |
IHC-P |
/ |
72838S |
SignalStain® Boost IHC Detection Reagent (HRP Rat) |
15ml |
IHC-P |
/ |
91196S |
Goat Anti-Mouse IgG Light-Chain Specific Antibody (HRP Conjugate) |
1ml |
W |
/ |
98164S |
Goat Anti-Rat IgG Light-Chain Specific Antibody (HRP Conjugate) |
1ml |
W |
/ |
96714S |
Goat Anti-Mouse IgG1 Fc gamma Specific Antibody (HRP Conjugate) |
1ml |
W |
/ |
33416S |
Goat Anti-Mouse IgG2a Fc gamma Specific Antibody (HRP Conjugate) |
1ml |
W |
/ |
43593S |
Goat Anti-Mouse IgG2b Fc gamma Specific Antibody (HRP Conjugate) |
1ml |
W |
/ |
56970S |
Goat Anti-Mouse IgG2c Fc gamma Specific Antibody (HRP Conjugate) |
1ml |
W |
/ |
75952S |
Goat Anti-Mouse IgG3 Fc gamma Specific Antibody (HRP Conjugate) |
1ml |
W |
/ |
RTK |
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38937S |
Ret (C31B4) Rabbit mAb (Biotinylated) |
100µl |
W |
H M |
Translational Control |
||||
73993S |
CPSF1 Antibody |
100µl |
W IP |
H M R Mk |
26168S |
PhosphoPlus ® GCN2 (Thr899) Antibody Duet |
1Kit |
/ |
|
47258S |
UAP56 (E7W7M) Rabbit mAb |
100µl |
W IP |
H M R Mk |
参考文献：
（1）Yang X, Qian K. Protein O-GlcNAcylation: emerging mechanisms and functions. Nat Rev Mol Cell Biol. 2017 Jul;18(7):452-465. doi: 10.1038/nrm.2017.22. Epub 2017 May 10. PMID: 28488703; PMCID: PMC5667541.
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