BMG多功能酶标仪国内用户出版物快报 (2024年8月)

>>>LARP1, an RNA-binding protein, participates in ovarian cancer cell survival by regulating mitochondrial oxidative phosphorylation in response to the influence of the PI3K/mTOR pathway

本期天然药相关研究成果显著增加，有5篇关于天然药药理学的研究论文，1篇天然药物结构和药效关系的论文，还有1篇中药药理学的研究论文。关于细胞能量代谢的研究论文有2篇。其中，吉林大学基础医学院病理生理学教育部重点实验室在专业学术期刊Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease发表的题为LARP1, an RNA-binding protein, participates in ovarian cancer cell survival by regulating mitochondrial oxidative phosphorylation in response to the influence of the PI3K/mTOR pathway的文章，对于肿瘤治疗的研究具有参考意义。

科研工作者使用BMG的CLARIOstar多功能酶标仪，使用 MitoXpress® Xtra-Oxygen Consumption 测定法测量细胞氧化磷酸化OCR，评估线粒体功能。采用ATP 生物发光测定试剂盒用于测量细胞中 ATP 的水平，使用BMG的Omega酶标仪测量发射光，将计数归一化为蛋白质浓度。CLARIOstar多功能酶标仪具有专属的细胞能量代谢检测配置、检测方案和分析方案，轻松实现高通量细胞能量代谢检测，Omega酶标仪能灵敏的检测发光信号，用于细胞活力检测。BMG的多功能酶标仪提供多种实验分析方案，是药物作用机理，疾病治疗靶点研究的有力工具。

（原文：https://www.sciencedirect.com/science/article/abs/pii/S0925443924004460）

Virulence, structure, and triadimefon sensitivity of the Puccinia striiformis f. sp. tritici population in Shaanxi Province, China

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Sympathetic neuropeptide Y protects from obesity by sustaining thermogenic fat

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Differential effect of lead and cadmium on mitochondrial function and NLRP3 inflammasome activation in human trophoblast

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Inoculation of Paraburkholderia sp. GD17 improves seedling growth and tolerance to Cadmium in Chinese cabbage

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Juzaowan Suppresses Glycolysis in Breast Cancer Cells by Inhibiting the STAT3/C-Myc Axis

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Tumor-associated macrophage-derived itaconic acid contributes to nasopharyngeal carcinoma progression by promoting immune escape via TET2

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Development of Nitric Oxide Releasing Oxoisoaporphines with Antidepressant Activities by Simultaneously Regulating MAO-A and SERT

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Functional characterisation and modification of a novel Kunitzin peptide for use as an anti-trypsin antimicrobial peptide against drug-resistant Escherichia coli

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Suppression of inner blood-retinal barrier breakdown and pathogenic Müller glia activation in ischemia retinopathy by myeloid cell depletion

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Carnosic acid, a novel food-source AT1R antagonist and its anti-hypertension mechanism华南师范大学生命科学学院广东省植物发育生物技术重点实验室

A novel evaluation mode of Nao An Capsules using multi-wavelength fusion fingerprint combined with quantitative analysis of multi-components by a single marker method and antioxidant activity

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The adhesin RadD enhances Fusobacterium nucleatum tumour colonization and colorectal carcinogenesis

上海交通大学医学院仁济医院

Synthesis of the Corrected Structure Assigned to Clonorosin B, an Alkaloid Obtained from the Soil-derived Fungus Clonostachys rosea YRS-06

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Oral secretions from striped stem borer (Chilo suppressalis) induce defenses in rice

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Repurposing cetylpyridinium chloride and domiphen bromide as phosphoethanolamine transferase inhibitor to combat colistin-resistant Enterobacterales

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An acidic polysaccharide promoting GLP-1 secretion from Dendrobium huoshanense protocorm-like bodies: Structure validation and activity exploration

合肥工业大学食品与生物工程学院

A diazeniumdiolate signal in Pseudomonas syringae upregulates virulence factors and promotes survival in plants

中国农业大学植物保护学院

Structural analysis of the human C5a-C5aR1 complex using cryo-electron microscopy

南昌大学江西医学院基础医学院教育部实体肿瘤靶向治疗基础研究与创新中心

Asiatic acid ameliorates doxorubicin-induced cardiotoxicity by promoting FPN-mediated iron export and inhibiting ferroptosis

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Synergism of colistin and globular endolysins against multidrug-resistant gram-negative bacteria

香港中文大学医学院药学院

The SPARC-related modular calcium binding 1 (Smoc1) regulated by androgen is required for mouse gubernaculum development and testicular descent

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Network Pharmacology Followed by Experimental Validation to Explore the Mechanism of Stigmasterol in Sangbaipi Decoction Regulating PI3K/Akt Signaling to Alleviate Acute Exacerbation of Chronic Obstructive Pulmonary Disease

杭州市同德医院肺重症医学科

Characterization of a KPC-84 harboring Klebsiella pneumoniae ST11 clinical isolate with ceftazidime-avibactam resistance

四川大学华西医院感染性疾病中心

Optimising corn (Zea mays) cob powder as an effective sorbent for diverse gel matrices: exploring particle size and powder concentration effects

南京农业大学食品科学与技术学院，肉类加工与质量控制重点实验室

ASA VI controls osteoarthritis in mice by maintaining mitochondrial homeostasis through Sirtuin 3

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Treatment with autophagic inhibitors enhances oligonol‑induced apoptotic effects in nasopharyngeal carcinoma cells

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The MondoA-dependent TXNIP/GDF15 axis predicts oxaliplatin response in colorectal adenocarcinomas

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Toxic effects of sodium hypochlorite as disinfectants on human bronchial epithelial cells

西安建筑科技大学环境与市政工程学院

LARP1, an RNA-binding protein, participates in ovarian cancer cell survival by regulating mitochondrial oxidative phosphorylation in response to the influence of the PI3K/mTOR pathway

吉林大学基础医学院病理生理学教育部重点实验室

Nonlinear Impacts of Temperature on Antibiotic Resistance in Escherichia coli

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New CDDO Arylboronate Ester Derivatives with High Selectivity and Low Toxicity

中国药科大学中药学院天然药物化学系天然药物国家重点实验室

Triggering of endoplasmic reticulum stress via ATF4-SPHK1 signaling promotes glioblastoma invasion and chemoresistance

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Dihydroartemisinin restores the immunogenicity and enhances the anticancer immunosurveillance of cisplatin by activating the PERK/eIF2α pathway

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